Brain imaging of 49 children aged 9-10 has found that those who were physically fit had a hippocampus significantly bigger (around 12%) than those who were not fit. Animal studies and those with older adults have shown that aerobic exercise increases the growth of new brain cells in the hippocampus. Physical fitness was measured by how efficiently the children used oxygen while running on a treadmill. Fitter children also did better on tests of relational (but not item) memory, and this association was directly mediated by hippocampal volume.
Physical fitness improves memory in children
Related News
Obesity linked to inflammation & impaired brain function
A mouse study has found that obese mice had high levels of interleukin 1 in both their blood and their brains, and this was associated with:
- high levels of inflammation,
- low levels of a biochemical important to synapse function, and
- impaired cognitive function.
Moreover, when fat was removed from the obese mice, interleukin levels dropped dramatically, and cognitive performance improved.
Putting obese mice on an exercise program had a similar effect, even though they didn’t lose weight — but they gained muscle and lost fat.
Importance of muscle for older adults
Data from the American National Health and Nutrition Examination Survey (NHANES) III, involving 3,659 individuals (men aged 55+; women 65+), has found that the more muscle mass older adults have, the less likely they are to die prematurely. The findings add to the growing evidence that overall body composition — and not the widely used body mass index (BMI) — is a better predictor of mortality.
http://www.eurekalert.org/pub_releases/2014-03/uoc--oab031314.php
Exercise improves heart function via mitochondria
A mouse study has found that long-term physical activity increased levels of two proteins in the mitochondria of their heart. It’s thought this might help explain why regular exercise improves cardiovascular health.
http://www.eurekalert.org/pub_releases/2014-02/cfgr-etc021114.php
Physical activity saves hippocampus in people at risk of Alzheimer's
A study involving 97 healthy older adults (65-89) has found that those with the “Alzheimer’s gene” (APOe4) who didn’t engage in much physical activity showed a decrease in hippocampal volume (3%) over 18 months. Those with the gene who did exercise showed no change in the size of their hippocampus, nor did those without the gene, regardless of exercise. Physical activity was classified as low if the participant reported two or fewer days per week of low intensity activity, such as no activity, slow walking or light chores.
Exercise beneficial for dementia
A new review from The Cochrane Library, based on six trials involving 289 people, has concluded that exercise can improve cognition and the ability of older people with dementia to carry out daily activities, such as walking short distances or getting up from a chair. However, there was no clear effect of exercise on depression in older people with dementia, and the reviewers say that more evidence is needed to understand how exercise could reduce the burden on family caregivers and health systems.
Gentle exercise during chemotherapy has significant cognitive benefits
A six-week study involving 619 cancer patients has found that those who took part in a simple home-based exercise program significantly reduced their cognitive impairment ('chemo-brain'). The EXCAP (Exercise for Cancer Patients) was developed by the researchers some years ago, and this evaluation was a phase III randomized study for early-stage chemotherapy patients. Half the group were given standard care (no exercise during chemotherapy), while the others were given instruction to walk daily and carry out low-to-moderate resistance band training for 10 minutes, 5 days a week.
Each hour of screen time linked to poorer grades
A study involving 845 secondary school students has revealed that each hour per day spent watching TV, using the internet or playing computer games at average age 14.5 years was associated with poorer GCSE grades at age 16. Additionally, each hour of daily homework and reading was linked to significantly better grades. Surprisingly, however, the amount of physical activity had no effect on academic performance.
Median screen time was four hours a day, of which around half was spent watching TV; median sedentary non-screen time (reading/homework) was 1.5 hours.
Chemo-brain: prevalence, why it happens, and how to help
Chemo-brain common among women with breast cancer
A study involving 581 breast cancer patients and 364 healthy age-matched people (mean age 53) has found that women with breast cancer reported significantly greater cognitive difficulties for up to six months after chemotherapy. Cognitive difficulties were evaluated using FACT-Cog, an assessment that examines a person's own perceived impairment as well as cognitive impairment perceived by others.
Both aerobic exercise & strength training improves older brains
A review of 39 studies investigating the effect of exercise on cognition in older adults (50+) confirms that physical exercise does indeed improve cognitive function in the over 50s, regardless of their cognitive status. Aerobic exercise, resistance training, multicomponent training and tai chi, all had significant effects. However, exercise sessions needed to be at least 45 minutes and moderate intensity.
Lifestyle changes can prevent cognitive decline even in genetically at-risk individuals
A Finnish study involving over 1000 older adults suggests that a counselling program can prevent cognitive decline even among those with the Alzheimer’s gene.
The study involved 1,109 older adults (aged 60-77) of whom 362 were carriers of the APOE4 gene. Some of the participants received regular lifestyle counselling (general health advice), while the rest received “enhanced” lifestyle counselling, involving nutrition counselling, physical and cognitive exercises, and support in managing the risk of cardiovascular diseases.
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