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Exposure to vehicle pollution bad for brains old and young

Two recent studies have come out implicating traffic pollutants as factors in age-related cognitive decline and dementia and as prenatal risk factors for attention problems.

A study in which mice were exposed to polluted air for three 5-hour sessions a week for 10 weeks, has revealed that such exposure damaged neurons in the hippocampus and caused inflammation in the brain. The polluted air was laden with particles collected from an urban freeway.

Another recent study found that, of 215 children, those whose cord blood showed high levels of combustion-related pollutants such as polycyclic aromatic hydrocarbons (PAH), had more attention (and anxiety) problems at ages 5 and 7. The children were born to nonsmoking African-American and Dominican women residing in New York City.

Reference

Morgan, T. E., Davis, D. A., Iwata, N., Tanner, J. A., Snyder, D., Ning, Z., … Finch, C. E. (2011). Glutamatergic Neurons in Rodent Models Respond to Nanoscale Particulate Urban Air Pollutants In Vivo and In Vitro. Environmental Health Perspectives. Retrieved from http://ehp03.niehs.nih.gov/article/info:doi/10.1289/ehp.1002973

Full text at http://ehponline.org/article/info:doi/10.1289/ehp.1002973

Perera, F. P., Wang, S., Vishnevetsky, J., Zhang, B., Cole, K. J., Tang, D., … Phillips, D. H. (2011). PAH/Aromatic DNA Adducts in Cord Blood and Behavior Scores in New York City Children. Environmental Health Perspectives. Retrieved from http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info%3Adoi%2F10.1289%2Fehp.1002705

Full text at http://ehponline.org/article/info:doi/10.1289/ehp.1002705

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