A study in which 60 young adult mice were trained on a series of maze exercises designed to challenge and improve their working memory ability (in terms of retaining and using current spatial information), has found that the mice improved their proficiency on a wide range of cognitive tests, and moreover better retained their cognitive abilities into old age.
Working memory training makes mice smarter
Reference
Light, K. R., Kolata, S., Wass, C., Denman-Brice, A., Zagalsky, R., & Matzel, L. D. (2010). Working Memory Training Promotes General Cognitive Abilities in Genetically Heterogeneous Mice. Current Biology. Retrieved from http://www.cell.com/current-biology/abstract/S0960-9822(10)00221-6