A 12-year study involving 1,221 married couples ages 65 or older (part of the Cache County (Utah) Memory Study) has revealed that husbands or wives who care for spouses with dementia are six times more likely to develop Alzheimer’s themselves than those whose spouses don't have it. The increased risk is of comparable size to having the ‘Alzheimer's gene’. The researchers speculate that the great stress of caregiving might be responsible for the increased dementia risk, emphasizing the need for greater caregiver support.
Looking after a spouse with dementia greatly increases your own risk of dementia
Related News
Better hygiene in wealthy nations may increase Alzheimer's risk
A comparison of Alzheimer’s prevalence across the world using 'age-standardized' data (which predict Alzheimer's rates if all countries had the same population birth rate, life expectancy and age structure) has found a strong correlation between national sanitation levels and Alzheimer's, with better hygiene associated with higher rates of Alzheimer’s.
Age-related drop in body temperature worsens Alzheimer's disease
Our bodies’ ability to regulate its temperature gets worse with age, along with a slowing metabolism. We also become more vulnerable to Alzheimer's as we age. A study compared mice genetically engineered to manifest Alzheimer's symptoms as they age with normal mice. They found that these transgenic mice were worse at maintaining their body temperature as they aged, with the difference reaching almost 1° Celsius by the age of 12 months.
Lower tau levels may obscure early Alzheimer’s in black patients
Data from 1,215 older adults, of whom 173 (14%) were African-American, has found that, although brain scans showed no significant differences between black and white participants, cerebrospinal fluid (CSF) showed significantly lower levels of the brain protein tau in African-Americans.
While both groups showed the same (expected) pattern of higher tau levels being associated with greater chance of cognitive impairment, the absolute amounts of tau protein were consistently lower in African-Americans.
Gut microbiome a risk factor for dementia
A Japanese study looking at 128 patients' fecal samples, found that fecal concentrations of ammonia, indole, skatole and phenol were higher in dementia patients compared to those without dementia, while levels of beneficial Bacteroides were lower in dementia patients.
https://www.eurekalert.org/pub_releases/2019-01/aha-it012519.php
Low social engagement linked to cognitive decline & dementia risk
Socially active 60-year-olds face lower dementia risk
Data from the Whitehall II study, tracking 10,228 participants for 30 years, found that increased social contact at age 60 is associated with a significantly lower risk of developing dementia later in life. Someone who saw friends almost daily at age 60 was 12% less likely to develop dementia than someone who only saw one or two friends every few months.
Healthy lifestyle associated with lower dementia risk regardless of genes
Data from 196,383 older adults (60+; mean age 64) in the UK Biobank found that a healthy lifestyle was associated with lower dementia risk regardless of genes.
Both an unhealthy lifestyle and high genetic risk were associated with higher dementia risk.
Gum disease bacteria may cause heart disease
A mouse study has found that introduction of oral bacteria into the bloodstream increased risk factors for atherosclerotic heart disease, including cholesterol and inflammation, suggesting that the same bacteria that cause gum disease also promotes heart disease. The findings are consistent with recent evidence that patients with gum disease are at higher risk for heart disease.
The findings were presented at the annual meeting of the American Society for Microbiology.
New cause of high blood pressure and heart disease discovered
Two studies help explain why kidney disease increases the risk of cardiovascular diseases such as high blood pressure and vascular calcification. The mediator seems to be a hormone called FGF23, which is sensitive to the level of phosphates in the body.
Phosphate rich foods include processed cheese, Parmesan, cola, baking powder and most processed foods.
http://www.eurekalert.org/pub_releases/2014-05/uovm-nco050514.php
One partner with diabetes raises the other’s risk
A meta-analysis of six studies from around the world, involving 75,498 couples, has found that a spouse had a 26% greater risk of developing diabetes if the other had been diagnosed with type 2 diabetes.
http://www.futurity.org/spouse-diabetes-raises-partners-risk/
Whole diet approach better for reducing cardiovascular risk
A review of research from 1957 to the present has concluded that a whole diet approach, and specifically Mediterranean-style diets, has more evidence for reducing cardiovascular risk than strategies that focus exclusively on reduced dietary fat.
http://www.eurekalert.org/pub_releases/2014-02/ehs-ssw020514.php
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