An imaging study involving 79 volunteers aged 44 to 88 has found lower volumes of gray matter and faster rates of decline in the frontal and medial temporal lobes of those who ranked high in neuroticism traits, compared with those who ranked high in conscientious traits. These are brain regions particularly affected by aging. The idea that this might occur derived from the well-established effects of chronic stress on the brain. This is the first study to investigate whether the rate and extent of cognitive decline with age is influenced by personality variables. Extraversion, also investigated, had no effect. The study does not, however, rule out the possibility that it is reduction in brain tissue in these areas that is affecting personality. There is increasing evidence that people tend to become more neurotic and less conscientious in early-stage Alzheimer's.
Personality may influence brain shrinkage in aging
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'Cocktail' for improved memory
A study has found that gerbils given a ‘cocktail’ of DHA, uridine and choline performed significantly better on learning and memory tests than untreated gerbils, and their brains had up to 70% more phosphatides (a type of molecule that forms cell membranes) than controls, suggesting that new synapses are forming. Some of the gerbils received all three compounds and some received only two; the improvements were greatest in those given all three. An earlier study had found that the treatment improved function in rats with cognitive impairment.
Age differences in the allocation of study time
Dunlosky, J. & Connor, L.T. (1997). Age differences in the allocation of study time account for age differences in memory performance. Memory and Cognition, 25, 691-700.
- It is well-established that older adults commonly need to practice more than younger adults to achieve the same level of performance.
- It may be that such age deficits in remembering are at least partly due to poorer monitoring of their learning.
It has been well-established that, compared to younger adults, older adults require more practice to achieve the same level of performance1. Sometimes, indeed, they may need twice as much2.
In the present study, two groups of adult subjects were given paired items to learn during multiple study-test trials. During each trial items were presented at the subject's pace. Afterwards the subjects were asked to judge how likely they were to be able to recall each item in a test.
It was found that people were very good at accurately judging the likelihood of their correct recall. Correlations between judgments and the amount of time the subjects studied the items suggested that people were monitoring their learning and using this to allocate study time.
However, older adults (with a mean age of 67) used monitoring to a lesser degree than the younger adults (with a mean age of 22), and the results suggested that part of the reason for the deficit in recall commonly found with older adults is due to this factor.
References
1. For a review, see Kausler, D.H. 1994. Learning and memory in normal aging. New York: Academic Press.
2. Delbecq-Derousné, J. & Beauvois, M. 1989. Memory processes and aging: A defect of automatic rather than controlled processes? Archives of Gerontology & Geriatrics, 1 (Suppl), 121-150.
Salthouse, T.A. & Dunlosky, J. 1995. Analyses of adult age differences in associative learning. Zeitschrift für Psychologie, 203, 351-360
Distinguishing normal cognitive decline from more serious disorders
Data from two longitudinal studies of older adults (a nationally representative sample of older adults, and the Alzheimer’s Disease Neuroimaging Initiative) has found that a brief cognitive test can distinguish memory decline associated with healthy aging from more serious memory disorders, years before obvious symptoms show up.
Moreover, the data challenge the idea that memory continues to decline through old age: after excluding the cognitively impaired, there was no evidence of further memory declines after the age of 69.
One Alzheimer's risk gene may begin to affect brains from childhood
A gene linked to Alzheimer's has been linked to brain changes in childhood. This gene, SORL1, has two connections to Alzheimer’s: it carries the code for the sortilin-like receptor, which is involved in recycling some molecules before they develop into amyloid-beta; it is also involved in lipid metabolism, putting it at the heart of the vascular risk pathway.
Daily crosswords linked to sharper brain in later life
Data from more than 17,000 healthy people aged 50 and over has revealed that the more regularly participants engaged with word puzzles, the better they performed on tasks assessing attention, reasoning and memory.
Study participants took part in online cognitive tests, as well as being asked how frequently they did word puzzles such as crosswords. There was a direct relationship between the frequency of word puzzle use and the speed and accuracy of performance on nine cognitive tasks.
Sleep problems linked to age-related cognitive problems
Chronic insomnia linked to memory problems
Data from 28,485 older Canadians (45+) found that those with chronic insomnia performed significantly worse on cognitive tests than those who had symptoms of insomnia without any noticable impact on their daytime functioning and those with normal sleep quality. The main type of memory affected was declarative memory (memory of concepts, events and facts).
Choline linked to better memory & healthier brains
Dietary choline linked to reduced dementia risk & better cognition
Data from a large, long-running Finnish study, involving some 2,500 men aged 42-60, has found that dietary intake of phosphatidylcholine was associated with a reduced risk of dementia (the risk was 28% lower in men with the highest intake compared to the lowest). Men with the highest intake of dietary phosphatidylcholine also excelled in tests measuring their memory and linguistic abilities.
The key sources of phosphatidylcholine in the study population's diet were eggs (39%) and meat (37%).
What causes word finding failures in young and older adults
Burke, D.M., MacKay, D.G., Worthley, J.S. & Wade, E. (1991). On the tip of the tongue: What causes word finding failures in young and older adults. Journal of Memory and Language, 30, 542-579.
- Failing to immediately retrieve well-known information does become more common with age.
- An increase in "tips of the tongue" is evident as early as the mid-thirties.
- The increase in memory failures applies to names of people and things; abstract words do not get harder to recall.
- The length of time before the missing word is recalled also increases with age.
- Older people tend to be less likely than younger people to actively pursue a missing word.
It is common for people to feel as they get older that they more frequently experience occasions when they cannot immediately retrieve a word they know perfectly well ("it's on the tip of my tongue").
Tips of the tongue (TOTs) do indeed increase with age, and this increase is evident as early as the mid-thirties. There are other differences however, in the TOT experiences as people age. For example, older adults are much more likely to "go blank" than either young or mid-age (35-45) adults. That is, younger adults are more likely to be able to retrieve some information about the target word.
At all ages, the most common type of word involved in TOTs is proper names. But while forgetting proper names and object names becomes more common as we get older, interestingly, abstract words are forgotten less.
The most common means of resolution at all ages is that the forgotten word simply "pops up", but as we get older, it takes longer before this happens. "Pop-ups" are relatively more common for older adults. It is suggested that this may be because they are less likely to actively attempt to retrieve the information. According to a questionnaire, older adults are more likely to simply relax and think about something else.
Memory complaints linked to higher risk of MCI & dementia
Data from 6257 older adults (aged 55-90) evaluated from 2005-2012 has revealed that concerns about memory should be taken seriously, with subjective complaints associated with a doubled risk of developing mild cognitive impairment or dementia, and subjective complaints supported by a loved one being associated with a fourfold risk. Complaints by a loved one alone were also associated with a doubled risk. Among those with MCI, subjective complaints supported by a loved one were associated with a threefold risk of converting to dementia.
Both aerobic exercise & strength training improves older brains
A review of 39 studies investigating the effect of exercise on cognition in older adults (50+) confirms that physical exercise does indeed improve cognitive function in the over 50s, regardless of their cognitive status. Aerobic exercise, resistance training, multicomponent training and tai chi, all had significant effects. However, exercise sessions needed to be at least 45 minutes and moderate intensity.
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