A preliminary study suggests that a regime of high doses of folic acid, B12 and B6 reduces levels of homocysteine in people with mild to moderate Alzheimer’s. A larger study, recruiting 400 participants from all over the U.S., is to be undertaken to assess whether such a vitamin regime can slow the progression of Alzheimer's disease. In the meantime, it is not advised that people take high doses of these vitamins, as there are possible side-effects, including peripheral nerve damage.
High-dose vitamin regime may help slow Alzheimer's
Reference
Bell, K., Sano, M., Aisen, P. S., Egelko, S., Andrews, H., Diaz-Arrastia, R., … Green, R. (2003). A pilot study of vitamins to lower plasma homocysteine levels in Alzheimer disease. The American Journal of Geriatric Psychiatry: Official Journal of the American Association for Geriatric Psychiatry, 11(2), 246-249. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/12611755
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