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Brain Regions

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A rat study provides further evidence that the conflicting findings on the benefit of estrogen therapy stem from the importance of timing.

The very large and long-running Women's Health Initiative study surprised everyone when it produced its finding that hormone therapy generally increased rather than decreased stroke risk as well as other health problems.

A monkey study finds that our very limited working memory capacity of around 4 items reflects two capacities of two items. The finding has practical implications for information presentation.

In the study, two rhesus monkeys were given a standard human test of working memory capacity: an array of colored squares, varying from two to five squares, was shown for 800 msec on a screen. After a delay, varying from 800 to 1000 msec, a second array was presented.

New study modifies findings that younger adults are better decision-makers by showing older adults are better when the scenarios involve multiple considerations.

Research has shown that younger adults are better decision makers than older adults — a curious result. A new study tried to capture more ‘real-world’ decision-making, by requiring participants to evaluate each result in order to strategize the next choice.

Two large studies respectively find that common health complaints and irregular heartbeat are associated with an increased risk of developing Alzheimer’s, while a rat study adds to evidence that stress is also a risk factor.

A ten-year study involving 7,239 older adults (65+) has found that each common health complaint increased dementia risk by an average of about 3%, and that these individual risks compounded.

A study has successfully countered reduced activity in the prefrontal cortex seen in older monkeys. Clinical trials are now investigating whether the drug can improve working memory in older humans.

A study comparing activity in the dorsolateral prefrontal cortex in young, middle-aged and aged macaque monkeys as they performed a spatial working memory task has found that while neurons of the young monkeys maintained a high rate of firing during the task, neurons in older animals showed slowe

A mouse study finds that gamma waves in the hippocampus, critically involved in learning, grow stronger as mice run faster.

I’ve always felt that better thinking was associated with my brain working ‘in a higher gear’ — literally working at a faster rhythm.

Two mice studies indicate that an increase in a protein involved in immune response may be behind the reduced ability of older brains to create new neurons, and that exercise produces a protein that helps protect against damage caused by illness, injury, surgery and pollutants.

In the first mouse study, when young and old mice were conjoined, allowing blood to flow between the two, the young mice showed a decrease in neurogenesis while the old mice showed an increase.

Learning two tasks or subjects one after another typically leads to poorer remembering of the first. A new study indicates the cause and suggests a remedy.

Trying to learn two different things one after another is challenging. Almost always some of the information from the first topic or task gets lost. Why does this happen?

New mouse research helps explain why the spacing effect occurs.

I’ve spoken often about the spacing effect — that it’s better to spread out your learning than have it all massed in a block.

New research suggests that successful retrieval depends not only on retrieval cues, but also on your preceding brain state.

What governs whether or not you’ll retrieve a memory? I’ve talked about the importance of retrieval cues, of the match between the cue and the memory code you’re trying to retrieve, of the strength of the connections leading to the code. But these all have to do with the memory code.

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