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Brain Regions

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Gist memory may be why false memories are more common in older adults
  • Gist processing appears to play a strong role in false memories.
  • Older adults rely on gist memory more.
  • Older adults find it harder to recall specific sensory details that would help confirm whether a memory is true.

Do older adults forget as much as they think, or is it rather that they ‘misremember’?

Brain tissue structure could explain link between fitness and memory
  • Brain scans of healthy young adults found that higher aerobic fitness was associated with greater hippocampal elasticity, which was a better predictor of cognitive performance than hippocampal volume.

A new MRI technique has revealed that it is the structural integrity of the hippocampus more than its size that reflects fitness and correlates with cognitive performance.

Trauma changes the brain even in those without PTSD
  • A review of previous research has compared brain activity in those with PTSD who experienced trauma, those who experienced trauma but didn't develop PTSD, and those who never experienced trauma.
  • Those who had PTSD had differential activity in two brain regions.
  • Those who had experienced trauma had differential activity in several brain regions associated with emotional regulation, regardless of whether they'd developed PTSD.

A meta-analysis of studies reporting brain activity in individuals with a diagnosis of PTSD has revealed differences between the brain activity of individuals with PTSD and that of groups of both trauma-exposed (those who had experienced trauma but didn't have a diagnosis of PTSD) and trauma-naïv

How yoga changes the brain

Brain scans have revealed that those who regularly practiced yoga had larger brain volume in the somatosensory cortex (maps the body), superior parietal cortex (involved in directing attention), visual cortex (perhaps because of visualization techniques), hippocampus, precuneus and the posterior

Size of hippocampus associated with PTSD therapy benefits
  • Size of that key memory region, the hippocampus, appears to be not simply a risk factor for PTSD, but also key to whether sufferers will respond positively to exposure therapy.

Following previous research showing that having a smaller hippocampus is associated with increased risk of PTSD, a study involving 40 participants with PTSD and 36 trauma-exposed healthy controls has found that those PTSD patients who responded to the treatment had larger hippocampi compared to t

Hippocampal iron increased in Alzheimer's disease

The hippocampus is damaged early in Alzheimer’s, while the thalamus is generally unaffected until the late stages.

Memory consolidation during sleep depends on coordinated brain activity
  • New research shows memory consolidation requires simultaneous replay with hippocampal 'ripples'. These may depend on deeper processing.

A study involving epilepsy patients who had electrodes implanted into their brain has revealed that memory consolidation during sleep doesn’t simply involve reactivation of the new memories.

Genes implicated in late-onset Alzheimer's disease

11 new genetic susceptibility factors for Alzheimer’s identified

Movie study confirms older people are more distractible

Idiosyncratic brain activity among older people watching a thriller-type movie adds to evidence that:

  • age may affect the ability to perceive and remember the order of events (explaining why older adults may find it harder to follow complex plots)
  • age affects the ability to focus attention and not be distracted
  • age affects the brain's connectivity — how well connected regions work together.

A study involving 218 participants aged 18-88 has looked at the effects of age on the brain activity of participants viewing an edited version of a 1961 Hitchcock TV episode (given that participants viewed the movie while in a MRI machine, the 25 minute episode was condensed to 8 minutes).

Mouse studies link physical exercise to increased synapses
  • A mouse study has found that a hormone released during physical activity protects synapses in the hippocampus.
  • Another mouse study found that short bursts of exercise promotes an increase in synapses in the hippocampus.

How exercise may protect against Alzheimer's

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