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A study involving 725 black and Dominican pregnant women living in New York and, later, their 3-year-old children, has found that children who were more highly exposed to PBO in personal air samples taken during the third trimester of pregnancy scored 3.9 points lower on the Bayley Mental Developmental Index than those with lower exposures. This is a similar effect size to that of lead exposure.

Shrinking of the frontal lobe has been associated with age-related cognitive decline for some time. But other brain regions support the work of the frontal lobe. One in particular is the cerebellum. A study involving 228 participants in the Aberdeen Longitudinal Study of Cognitive Ageing (mean age 68.7) has revealed that there is a significant relationship between grey matter volume in the cerebellum and general intelligence in men, but not women.

Two experiments involving a total of 191 volunteers have investigated the parameters of sleep’s effect on learning. In the first experiment, people learned 40 pairs of words, while in the second experiment, subjects played a card game matching pictures of animals and objects, and also practiced sequences of finger taps. In both groups, half the volunteers were told immediately following the tasks that they would be tested in 10 hours. Some of the participants slept during this time.

In a study in which 78 healthy elders were given 5 different tests and then tested for cognitive performance 18 months later, two tests combined to correctly predict nearly 80% of those who developed significant cognitive decline. These tests were a blood test to identify presence of the ‘Alzheimer’s gene’ (APOE4), and a 5-minute fMRI imaging scan showing brain activity during mental tasks.

A study involving 171 sedentary, overweight 7- to 11-year-old children has found that those who participated in an exercise program improved both executive function and math achievement. The children were randomly selected either to a group that got 20 minutes of aerobic exercise in an after-school program, one that got 40 minutes of exercise in a similar program, or a group that had no exercise program. Those who got the greater amount of exercise improved more.

Brain images of 16 participants in an 8-week mindfulness meditation program, taken two weeks before and after the program, have found measurable changes in brain regions associated with memory, sense of self, empathy and stress. Specifically, they showed increased grey-matter density in the left hippocampus, posterior cingulate cortex, temporo-parietal junction, and cerebellum, as well as decreased grey-matter density in the amygdala. Similar brain scans of a control group of non-meditators (those on a waiting list for the program) showed no such changes over time.

I’ve talked about the importance of retrieval practice at length, so I’m pleased to report on the latest study to confirm its value. Indeed, this study demonstrates that practicing retrieval is a more effective strategy than elaborative studying.

Contrary to previous laboratory studies showing that children with autism often demonstrate outstanding visual search skills, new research indicates that in real-life situations, children with autism are unable to search effectively for objects. The study, involving 20 autistic children and 20 normally-developing children (aged 8-14), used a novel test room, with buttons on the floor that the children had to press to find a hidden target among multiple illuminated locations. Critically, 80% of these targets appeared on one side of the room.

A study involving 360 patients with degenerative dementia (109 people with dementia with Lewy bodies (DLB) and 251 with Alzheimer's) and 149 matched controls, has found that 48% of those with DLB had previously suffered from adult ADHD. This compares with 15% found in both the control group and the group with Alzheimer's. DLB tends to be under-diagnosed, but is thought to account for around 10% of dementia cases in older people.

ADHD and DLB are thought to both involve the same neurotransmitter pathway problems.

Increased awareness and changes in diagnostic criteria can’t entirely explain the massive increase in autism — the U.S. Centers for Disease Control reported a 57% increase between 2002 and 2006. Another factor may involve environmental pollutants.