Lesions of the brain microvessels include white-matter hyperintensities and the much less common silent infarcts leading to loss of white-matter tissue. White-matter hyperintensities are common in the elderly, and are generally regarded as ‘normal’ (although a recent study suggested we should be less blasé about them — that ‘normal’ age-related cognitive decline reflects the presence of these small lesions).
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A study involving 38 people suffering from mild traumatic brain injury (TBI) has found that those receiving acupressure treatments from trained experts (eight treatments over 4 weeks) scored significantly better on tests of working memory compared to those who received treatments from the same experts on places on the body that are not considered to be acupressure points.
We’ve all experienced the fading of our ability to concentrate when we’ve been focused on a task for too long. The dominant theory of why this should be so has been around for half a century, and describes attention as a limited resource that gets ‘used up’. Well, attention is assuredly a limited resource in the sense that you only have so much of it to apply. But is it limited in the sense of being used up and needing to refresh? A new study indicates that it isn’t.
A new molecular compound derived from curcumin (found in turmeric) holds promise for treating brain damage caused by stroke. Turmeric has a long history of use in Ayurvedic and Chinese traditional medicine. However, curcumin has several important drawbacks as far as treating stroke is concerned — mainly because it can’t cross the blood-brain barrier. The new compound can.
The new label of ‘metabolic syndrome’ applies to those having three or more of the following risk factors: high blood pressure, excess belly fat, higher than normal triglycerides, high blood sugar and low high-density lipoprotein (HDL) cholesterol (the "good" cholesterol). Metabolic syndrome has been linked to increased risk of heart attack.
In a study designed to minimize flaws found in many earlier studies, a comparison of 52 illicit ecstasy users and 59 matched non-users, aged 18–45 years, revealed little evidence of decreased cognitive performance in ecstasy users, with the exception of poorer strategic self-regulation, possibly reflecting increased impulsivity. This may reflect a pre-existing state, rather than being a consequence of the drug.
A study involving 725 black and Dominican pregnant women living in New York and, later, their 3-year-old children, has found that children who were more highly exposed to PBO in personal air samples taken during the third trimester of pregnancy scored 3.9 points lower on the Bayley Mental Developmental Index than those with lower exposures. This is a similar effect size to that of lead exposure.
Shrinking of the frontal lobe has been associated with age-related cognitive decline for some time. But other brain regions support the work of the frontal lobe. One in particular is the cerebellum. A study involving 228 participants in the Aberdeen Longitudinal Study of Cognitive Ageing (mean age 68.7) has revealed that there is a significant relationship between grey matter volume in the cerebellum and general intelligence in men, but not women.
Two experiments involving a total of 191 volunteers have investigated the parameters of sleep’s effect on learning. In the first experiment, people learned 40 pairs of words, while in the second experiment, subjects played a card game matching pictures of animals and objects, and also practiced sequences of finger taps. In both groups, half the volunteers were told immediately following the tasks that they would be tested in 10 hours. Some of the participants slept during this time.
Data from the Baltimore Longitudinal Study on Aging, begun in 1958, has revealed that seniors with hearing loss are significantly more likely to develop dementia than those who retain their hearing. The study involved 639 people whose hearing and cognitive abilities were tested between 1990 and 1994, then re-tested every one to two years. By 2008, 58 (9%) of them had developed dementia (37 of which were Alzheimer’s).