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A computerized self test (CST) has been developed that is 96% accurate in diagnosing Alzheimer’s and MCI-A (compared to 71% for the MMSE and 69% for the Mini-Cognitive — tests currently in use).
Data from 625 elderly Americans, followed for an average of 8.5 years, has revealed that those with very good or excellent vision at the beginning of the study had a 63% reduced risk of dementia over the study period.
A new test has been developed that measures amyloid-beta oligomers in the cerebrospinal fluid, promising a reliable means of early diagnosis.
An analysis technique using artificial neural networks has revealed that the most important factors for predicting whether amnestic mild cognitive impairment (MCI-A) would develop into Alzheimer’s within 2 years were hyperglycemia, female gender and having the APOE4 gene (in that order).
Data from over 900 community-dwelling older adults participating in the Rush Memory and Aging Project has found that greater purpose in life was associated with a substantially reduced risk of developing Alzheimer's disease, as well as a reduced risk of mild cognitive impairment and a slower rate
By following 597 Alzheimer’s patients over 15 years, researchers have determined that a simple progression rate can be calculated at the initial visit, using symptom onset and present performance, and that this can reliably identify slow, intermediate and rapid progression.
Midlife hypertension has been confirmed as a risk factor for the development of dementia in late life, but there have been conflicting findings about the role of late-life hypertension.
A study involving 57 cognitively healthy older adults has found that those who showed decreased memory performance two years later (20 of the 57) had higher baseline levels of phosphorylated tau231 in the cerebrospinal fluid, and more atrophy in the medial temporal lobe.
Rapamycin, a drug that keeps the immune system from attacking transplanted organs, was recently found to extend the life span of aged research mice.
Data from 330 participants in The 90+ Study, of whom 70% were women, has revealed an overall annual incidence rate of 18.2% for dementia, rising from 12.7% per year in the 90-94 age group, to 21.2% in the 95-99 age group and 40.7% per year in the 100+ age group.