Another study showing the cognitive benefits of meditation has revealed benefits to perception and attention. The study involved 30 participants attending a three-month meditation retreat, during which they attended group sessions twice a day and engaging in individual practice for about six hours a day. The meditation practice involved sustained selective attention on a chosen stimulus (e.g., the participant’s breath).
Latest Research News
We know that lead damages the brain, and that it does so by somehow affecting the release of neurotransmitters at synapses (the process by which neurons pass messages on). Now a new study explains exactly what lead does. Apparently, during the formation of synapses, lead lowers the levels of key proteins involved in neurotransmitter release (synaptophysin and synaptobrevin), and reduces the number of fast-releasing sites. These effects may occur through the inhibition of the NMDA receptor (which produced similar effects), disrupting the release of BDNF.
The largest ever trial of fish oil supplements has found no evidence that they offer benefits for cognitive function in older people. The British study enrolled 867 participants aged 70-80 years, and lasted two years. After two years, those receiving fish oil capsules had significantly higher levels of omega-3 fatty acids in their blood than those receiving placebo capsules. However, cognitive function did not decline in either group over the period. The researchers caution that it may be that more time is needed for benefits to show.
The Phase II clinical trial of a treatment using naturally occurring antibodies (IGIV) has achieved significantly lower rates of ventricular enlargement (6.7% vs 12.7% per year) and less whole-brain atrophy (1.6% vs 2.2% per year) than control subjects who initially received placebo. The trial ran for 18 months and involved 24 patients with mild to moderate Alzheimer's disease, of whom 16 received IGIV once or twice a month for the whole period, and 8 received a placebo for the first 6 months.
An intriguing set of experiments showing how you can improve perception by manipulating mindset found significantly improved vision when:
As we all know, being interrupted during a task greatly increases the chance we’ll go off-kilter (I discuss the worst circumstances and how you can minimize the risk of mistakes in my book Planning to remember). Medication errors occur as often as once per patient per day in some settings, and around one-third of harmful medication errors are thought to occur during medication administration.
Another gene has been identified that appears to increase risk of Alzheimer’s. The gene, MTHFD1L, is located on chromosome six. Comparison of the genomes of 2,269 people with late-onset Alzheimer's disease and 3,107 people without the disease found those with a particular variation in this gene were almost twice as likely to develop Alzheimer's disease as those people without the variation. The gene is involved in influencing the body's levels of homocysteine (high levels are known to be a strong risk factor), and have also been implicated in coronary artery disease.
Visual working memory, which can only hold three of four objects at a time, is thought to be based on synchronized brain activity across a network of brain regions. Now a new study has allowed us to get a better picture of how exactly that works. Both the maintenance and the contents of working memory were connected to brief synchronizations of neural activity in alpha, beta and gamma brainwaves across frontoparietal regions that underlie executive and attentional functions and visual areas in the occipital lobe.
A study involving 136 healthy institutionalized infants (average age 21 months) from six orphanages in Bucharest, Romania, has found that those randomly assigned to a foster care program showed rapid increases in height and weight (but not head circumference), so that by 12 months, all of them were in the normal range for height, 90% were in the normal range for weight, and 94% were in the normal range of weight for height. Caregiving quality (particularly sensitivity and positive regard for the child, including physical affection) positively correlated with catch-up.
The American Academy of Neurology has updated its guidelines on when people with dementia should stop driving. While the guidelines point out that this decision is a complex one that should be made by a doctor using the Clinical Dementia Rating scale, they also supported caregivers’ instincts, which have been found to often be correct. For caregivers and family members, the following warning signs are identified: