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Latest Research News

Sleep, as I have said on many occasions, helps your brain consolidate new memories. I have reported before on a number of studies showing how sleep helps the learning of various types of new information. Most of those studies have looked at procedural learning (learning new skills), or verbal learning. A new study adds to these by looking at face-name associations.

A review of 39 studies investigating the effect of exercise on cognition in older adults (50+) confirms that physical exercise does indeed improve cognitive function in the over 50s, regardless of their cognitive status. Aerobic exercise, resistance training, multicomponent training and tai chi, all had significant effects. However, exercise sessions needed to be at least 45  minutes and moderate intensity.

A number of studies have found that physical exercise can help delay the onset of dementia, however the ability of exercise to slow the decline once dementia has set in is a more equivocal question. A large new study answers this question in the negative.

A study involving 4,050 people with late-onset Alzheimer's disease (mean age 80) has classified them into six groups based on their cognitive functioning at the time of diagnosis. A genetic study found two of the groups showed strong genetic associations.

A mouse study helps explain why vitamin D is so important for cognition. After 20 weeks of no vitamin D, the healthy adult mice showed a significant decline in their ability to remember and learn. They also showed a pronounced reduction in perineuronal nets in the hippocampus. These nets provide a supportive scaffold around certain neurons, stabilising their connections with other neurons. There was also a substantial reduction in both the number and strength of connections between neurons.

A study involving 110 lean and healthy students (aged 20-23) found that those randomly assigned to a high energy western-style diet for a week performed worse on a memory test compared to those who ate their normal healthy diet. Moreover, those on the unhealthy diet then showed a greater tendency to eat more sugary foods.

It is common for people to feel as they get older that they more frequently experience occasions when they cannot immediately retrieve a word they know perfectly well ("it's on the tip of my tongue").

Type 2 diabetes greatly increases a person's risk of developing cardiovascular disease, but a new study shows that cardiovascular risk factors such as elevated blood pressure and cholesterol levels differ significantly between men and women with diabetes.

The study, involving 680 diabetics, found that blood pressure and LDL cholesterol levels were significantly higher in women, and women were significantly less likely to have these factors under control. Some 17% of men had control of these factors, compared to 6% of women.

A large long-running study has found that eating a diet rich in animal proteins during middle age makes you four times more likely to die of cancer than a low-protein diet (a mortality risk factor comparable to smoking), 74% more likely to die of any cause within the 20-year study period, and five times more likely to die of diabetes. Even those eating a moderate amount of protein had much higher levels of mortality risk.

However, a high or moderate protein diet is helpful for those over 65, when levels of the growth hormone IGF-I drop off dramatically.

Analyses of cerebrospinal fluid from 15 patients with Alzheimer's disease, 20 patients with mild cognitive impairment, and 21 control subjects, plus brain tissue from some of them, has found that those with Alzheimer’s had lower levels of a particular molecule involved in resolving inflammation. These ‘specialized pro-resolving mediators’ regulate the tidying up of the damage done by inflammation and the release of growth factors that stimulate tissue repair. Lower levels of these molecules also correlated with a lower degree of cognitive function.