subiculum

a substructure of the hippocampus, active during the retrieval of newly-learned face-name associations (but less so as retrieval became more practiced). (also see dentate gyrus and cornu ammonis)

Inflamed iron-containing cells found in Alzheimer's brains

A post-mortem study of five Alzheimer's and five control brains has revealed the presence of iron-containing microglia in the subiculum of the Alzheimer's brains only. The subiculum lies within the hippocampus, a vital memory region affected early in Alzheimer's. None of the brains of those not diagnosed with Alzheimer's had the iron deposits or the microglia, in that brain region, while four of the five Alzheimer's brains contained the iron-containing microglia.

How family circumstance impacts learning and memory in children

Quarter of British children performing poorly due to family disadvantage

A British study involving over 18,000 very young children (aged 9 months to 5 years) has found that those exposed to two or more “disadvantages” (28% of the children) were significantly more likely to have impaired intellectual development, expressed in a significantly reduced vocabulary and behavioral problems.

Specific hippocampal atrophy early sign of MCI & Alzheimer's

A three-year study involving 169 people with mild cognitive impairment has found that those who later developed Alzheimer's disease showed 10-30% greater atrophy in two specific locations within the hippocampus, the cornu ammonis (CA1) and the subiculum.

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